New research exposes the molecular switches that let some cancers shapeshift and reveals how they might finally be stopped. Certain cancers are extremely difficult to treat, and carcinomas are among ...

Researchers have identified a subset of brain cells in mice that act as the master regulators of urination. Urination requires the coordinated function of two units of the lower urinary tract. The ...

Immune cell trapping during allergic responses Mast cells, residing in tissues and critical for initiating inflammation, are filled with granules containing pro-inflammatory substances. These granules ...

Please provide your email address to receive an email when new articles are posted on . Barzolvolimab is an anti-KIT monoclonal antibody, and mast cells need KIT to survive. Weekly hive and itch ...

In early 2020, Wynde Dyer walked into the house that would transform her life. The Central California ranch sat on a cul-de-sac of gated homes and glittering aquamarine pools. It boasted private ...

WASHINGTON, Nov 20 (Reuters) - Researchers announced on Tuesday that they had found a way to make powerful human embryonic stem cells without using cloning technology and without making a human embryo ...

New research at the University of Minnesota and elsewhere suggests that adults carry a reservoir of ''master cells'' inside their bone marrow that - like stem cells taken from human embryos - are ...

– Data provide insights on the signaling pathways involved with AK006 mast cell inhibition –– AK006 has a distinct mechanism of action that leads to broad inhibitory effects on mast cells – The ...

Advanced systemic mastocytosis (advSM) is a rare and serious form of systemic mastocytosis, a blood disorder that involves the overproduction of mast cells. Mast cells are a type of white blood cell ...

This scanning electron microscopy image captures the moment where degranulating mast cells (pseudo-colored in sepia) attract and start to incorporate living neutrophils (pseudo-colored in cyan), ...