Polycystic kidney disease (PKD) is a genetic disorder marked by the growth of many fluid-filled sacs (cysts) in your kidneys. These cysts can grow to replace normal kidney tissue over time, leading to ...

Polycystic kidney disease (PKD) causes round, fluid-filled sacs called cysts to grow in your kidneys. These cysts can cause your kidneys to enlarge and function poorly. People with PKD can also ...

PKD is mainly caused by mutations in the PKD1 and PKD2 genes, affecting polycystin proteins. Disrupted signaling pathways, like cAMP and vasopressin, are major drivers of cyst growth. Tolvaptan is ...

A newly engineered antibody can penetrate kidney cysts and interrupt the growth signals that drive polycystic kidney disease. Early tests show it selectively kills cyst cells while leaving healthy ...

Credit: Getty Images The inaugural ADPKD guideline introduces new ADPKD nomenclature and offers updated recommendations on therapies to slow disease progression. The inaugural ADPKD guideline from ...

Kidney cancer is moderately common, the sixth-most prevalent cancer diagnosis for men and women. Benjamin L. Maughan, MD, PharmD, assistant professor in the division of medical oncology, answers ...

Symptoms of stage 3 RCC vary; some patients experience blood in the urine, flank pain, fatigue, weight loss, or a palpable ...