Membrane proteins are key targets for many drugs. They are located between the outside and inside of our cells. Some of them, called 'transporters', move certain substances in and out of the cellular ...

The plasma membrane is what isolates the cell’s interior from its surroundings. It is made up of a lipid bilayer and other macromolecules, such as carbohydrates, glycoproteins, and membrane proteins, ...

A long-standing mystery in bile acid biology has been solved. Bile acids are often introduced as digestion helpers, but they are also powerful chemical messengers that help coordinate metabolism ...

Pi plays crucial metabolic and structural roles in living organisms. It is essential for bioenergetics (ATP, GTP), metabolic regulation through glycolysis and oxidative phosphorylation, intercellular ...

Biophysicists have designed a new cell-like transport system that represents an important milestone on the road to artificial cells. Creating artificial cells with life-like characteristics out of a ...

Using cryo-EM structure determination, molecular dynamics simulations, and electrophysiological analyses, researchers from the Shanghai Institute of Materia Medica of the Chinese Academy of Sciences ...